SubtiBank SubtiBank
Version comparison:

2017-05-09 15:36:332025-05-11 16:23:54

locus

BSU08730

BSU_08730

geneLength

435

438

product

transcriptional repressor (Fur family)

transcriptional repressor ([SW|Fur family])

ec

outlinks

bsu

BSU08730

BSU_08730

Gene

Coordinates

944,487 → 944,924

944,487 944,924

The protein

Protein family

[SW|Fur family]

[SW|Fur family] (according to UniProt)

The protein

Paralogous protein(s)

[[protein|Zur]], [[protein|Fur]]

[[this]]

The protein

[SW|Cofactors]

contains an Fe(2+) at the regulatory site and Zn(2+) [Pubmed|22797754]

contains an Fe2+ at the regulatory site and Zn2+ [Pubmed|22797754]

The protein

Effectors of protein activity

responds to the presence of hydrogen peroxide

responds to the presence of hydrogen peroxide [pubmed|29738773]

Biological materials

Mutant

MGNA-A258 (ygaG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/258 NBRP B. subtilis, Japan]

HB0509 (spc), available in [SW|John Helmann]'s and [SW|Jörg Stülke]'s labs, also GP868 (''fur::mls'', ''perR::spc'').

1A903 ( ''perR''::''kan''), [Pubmed|12029044], available at the [http://bgsc.org/getdetail.php?bgscid=1A903 Bacillus Genetic Stock Center]

BKE08730 (''perR''::''erm trpC2'') is available at the [http://bgsc.org/ Bacillus Genetic Stock Center]

GP3171 [[gene|perR]]::kan trpC2 available in [SW|Jörg Stülke]'s lab

MGNA-A258 (ygaG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/258 NBRP B. subtilis, Japan]

HB0509 (spc), available in [SW|John Helmann]'s and [SW|Jörg Stülke]'s labs, also GP868 (''fur::mls'', ''perR::spc'').

1A903 ( ''perR''::''kan''), [Pubmed|12029044], available at the [http://bgsc.org/getdetail.php?bgscid=1A903 Bacillus Genetic Stock Center]

BKE08730 ([[gene|ahpC]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE08730 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCGTCATGCACCTCTCT, downstream forward: _UP4_TAAAAATAAGCTGACCGCAC

BKK08730 ([[gene|ahpC]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK08730 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCGTCATGCACCTCTCT, downstream forward: _UP4_TAAAAATAAGCTGACCGCAC

Labs working on this gene/protein

[SW|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]

References

Reviews

19575568, 19508286, 20094649, 20977351, 22797754, 25160631, 26070785, 26677871

19575568, 19508286, 20094649, 20977351, 22797754, 25160631, 26070785, 26677871, 28938859

References

Original Publications

8932315, 18487332, 14563870, 16766519, 17158660, 12486061, 11532148, 12180919, 16166527, 15231799, 12029044, 10913706, 21398634, 9701813, 16541078, 12029044, 11532148, 12029044, 19508285, 22194458, 23645680, 23057863, 23934352, 25486128, 26261021, 27920297, 27935957, 28104400

8932315, 18487332, 14563870, 16766519, 17158660, 12486061, 11532148, 12180919, 16166527, 15231799, 12029044, 10913706, 21398634, 9701813, 16541078, 12029044, 11532148, 12029044, 19508285, 22194458, 23645680, 23057863, 23934352, 25486128, 26261021, 27920297, 27935957, 28104400, 11918677, 29738773, 31988078

labs

[SW|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]